Yifei Jeff Dong

Dr. Yifei Jeff Dong PhD

Hotchkiss Brain Institute
University of Calgary
Calgary | Canada

Yifei Jeff Dong, PhD, is currently a postdoctoral fellow at the Department of Clinical Neuroscience at the Hotchkiss Brain Institute and the University of Calgary in Canada.

Dr. Dong completed a PhD degree in 2018 with Dr. Pauline Johnson at the University of British Columbia in Canada. His thesis focused on how the extracellular matrix molecule hyaluronan, and its receptor CD44 regulate lung alveolar macrophage functions in homeostasis and during inflammation. He then joined the laboratory of Dr. V. Wee Yong as a postdoctoral fellow to study the neuroimmunology of MS. His recent work identified oxidized phosphatidylcholine, a biomarker of oxidative stress in MS lesions, are potent mediators of neurodegeneration in the CNS that require microglia for removal. His current research focuses on how ageing perturbs the microglia transcriptomes and functions to become less protective and even injurious, and how this may contribute to the acceleration of neurodegeneration and MS disease progression in ageing individuals.

Dr. Dong is grateful for postdoctoral fellowship funding support from the Canadian Institutes of Health Research, the MS Society of Canada, the Hotchkiss Brain Institute, and the Alberta MS Network.